Wound Healing/Injury Recovery

BPC-157/TB-500

BPC 157

BPC 157 is a partial 15 amino acids sequence of the body protection compound (BPC) that is discovered in and isolated from human gastric juice.

Research has shown BPC 157 has considerable biological healing properties. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including tendons, muscles, nervous system, and ligaments. This peptide can be very useful to athletes or just the average person who has daily aches, pains, or injury.

Those who suffer from discomfort due to muscle sprains, tears and damage may benefit from treatment with this peptide. It can also help aid skin burns to heal at a faster rate and increase blood flow to damaged tissues.

BPC 157 can be given in addition to Thymosin Beta-4 for a limited time to enhance their combined efficacy. Thymosin is a hormone secreted from the thymus. Its primary function is to stimulate the production of T cells, which are an important part of the immune system. Thymosin also assists in the development of B cells to plasma cells to produce antibodies. The predominant form of thymosin, Thymosin Beta 4, is an actin, a cell building protein. One of the main mechanisms of action of Thymosin Beta-4 is its regulation of actin. This cell-building protein is an essential component of cell structure and movement which leads to its role in tissue repair.

Thymosin Beta-4 has been found to play an important role in protection, regeneration, and remodeling of injured or damaged tissues. After an injury, Thymosin Beta-4 is released by platelets and numerous other types of cells to protect the most damaged cells and tissues and to reduce inflammation and microbial growth.

Potential Benefits

·        Accelerated wound healing (muscle, ligament, tendon, nerve)

·        Anti-inflammatory

·        Has been shown to decrease pain in damaged areas

·        BPC 157 increases growth hormone receptors

·        Promotes the outgrowth of tendon fibroblast

·        Promotes cell survival under stress

·        Promotes the migration of tendon fibroblasts

·        Improves digestive function

·        Protects and heals inflamed intestinal epithelium (leaky gut)

·        It has also been shown to help in Inflammatory bowel disease

·        Protects liver from toxic insults (alcohol, antibiotics, etc)

·        May decrease Blood Pressure

Potential Side Effects

Potential BPC-157 side effects typically emerge in patients who use the peptide for an extended period and in some patients with certain pre-existing conditions. The most common side effects reported by patients include:

  • Nausea

  • Dizziness

  • Hot flashes

  • Injection site redness

  • Cannot be used by professional athletes

Thymosin Beta-4

Potential Benefits

·        Calms muscle spasm

·        Improved muscle tone

·        Increased exchange of substances between cells

·        Encourages tissue repair

·        Stretches connective tissue

·        Helps maintain flexibility

·        Reduced inflammation of tissue in joints

·        Encourages the growth of new blood cells in tissue

·        Increased endurance and strength

·        Prevents the formation of adhesions and fibrous bands in muscles, tendons, and ligaments

Benefits

Recent studies have revealed that the first gene to be upregulated after an injury is the Thymosin Beta-4 gene. As the body begins the recovery process, Thymosin Beta-4 aids in the creation of new vessels in the injured area, which carry blood, nutrients, and reparative substances to the site. Thymosin Beta-4 also has anti-inflammatory properties and works to decrease the amount of inflammatory substances, called cytokines. Inflammation plays a large role in many of the symptoms associated with a number of other conditions (i.e., Lyme disease, CFS, FM, autoimmune diseases, infections, etc.).

The discovery of the role of Thymosin Beta-4 in the process of immune regulation has led to its use as a valuable therapeutic agent. Thymosin Beta-4 has been used in the treatment of HIV, AIDS, Influenza, colds, and various infections. It has been utilized in the management of various inflammatory conditions, as well as part of treatment following a heart attack due to its cardio and neuroprotective effects.

Potential Side Effects

Thymosin Beta-4 is deemed both safe and effective, with minimal side effects associated. If side effects do occur, symptoms usually include reddening, pain, and discomfort at the injection site. Headaches and lethargy are also possible in first-dose injections, but these symptoms subside promptly.